Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection (Merkl & Knipe, 2019)
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We study the molecular and cellular biology of herpes simplex virus productive and latent infection and the mechanism of the host immune response to HSV. We also have been studying a candidate genital herpes vaccine that we have developed, and we are constructing and studying HSV recombinants as vaccine vectors for AIDS, SARS, West Nile and anthrax vaccines. Please look at the material on our website describing research projects, publications, lab pictures, and contact me if you are interested in participating in this research.

With best wishes,

David M. Knipe, Ph.D.
Higgins Professor of Microbiology and Molecular Genetics

C.V.