Department of Microbiology and Molecular Genetics
Harvard Medical School
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Welcome to the Knipe Lab

Infected Cell Nucleus

Photo by Martha Simpson-Holley

We study the molecular and cellular biology of herpes simplex virus productive and latent infection and the mechanism of the host immune response to HSV. We also have been studying a candidate genital herpes vaccine that we have developed, and we are constructing and studying HSV recombinants as vaccine vectors for AIDS, SARS, West Nile and anthrax vaccines. Please look at the material on our website describing research projects, publications, lab pictures, and contact me if you are interested in participating in this research.

With best wishes,

David Knipe
Higgins Professor of Microbiology and Molecular Genetics
Chair, Harvard Virology Program

If you are interested in graduate study in my lab or the Harvard Virology Program, please see the following link:
http://www.hms.harvard.edu/dms/virology/

Lab Member Resources

Recent Publications:

Cliffe, A.R., D.S. Garber, D. M. Knipe.  2009. Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterchromtain on the latent genome. Journal of Virology.  83: 8182-90.