Department of Microbiology
Blavatnik Institute
Harvard Medical School
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ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress (Cabral et al., 2018)





Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection (Merkl & Knipe, 2019)



We study the molecular and cellular biology of herpes simplex virus productive and latent infection and the mechanism of the host immune response to HSV. We also have been studying a candidate genital herpes vaccine that we have developed, and we are constructing and studying HSV recombinants as vaccine vectors for AIDS, SARS, West Nile and anthrax vaccines. Please look at the material on our website describing research projects, publications, lab pictures, and contact me if you are interested in participating in this research.

With best wishes,

David M. Knipe, Ph.D.
Higgins Professor of Microbiology and Molecular Genetics

C.V.

Donate to the Knipe Lab:
Gifts can be made using the Harvard Online Giving Form for Harvard Medical School. To ensure that your gift is directed to the Knipe Lab, please choose "Other" in the "Select a Fund" drop-down menu and enter Knipe Lab Research Fund (520-362612) in the "Other Fund Name" field. Your gift will then be directed to the Knipe Lab Research Fund.